Tuberculosis (TB) and other important infectious bacteria can be diagnosed by a handheld diagnostic device.
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| Tuberculosis Bacteria |
The scientist explain portable devices that combine microfluidic technology with nuclear magnetic resonance (NMR) to not only diagnose these important infections but also determine the presence of antibiotic resistant bacterial strains. Further said that "Rapidly identifying the pathogen responsible for an infection and testing for the presence of resistance are critical not only for diagnosis but also for deciding which antibiotics to give a patient."
Above described methods allow them to do this in two to three hours, a immense improvement over standard culturing practice, which can get as much as two weeks to provide a diagnosis.
The system described in above detects DNA from the tuberculosis bacteria in small sputum samples. After DNA is extracted from the sample and detects any TB bacterial DNA present in the sample.
The device was sensitive enough to detect as few as one or two bacteria in a 10 ml blood sample and to accurately estimate bacterial load. Testing the system on blood samples from patients with known infections accurately identified the particular bacterial species in less than two hours and also detected two species that had not been identified with standard culture techniques.




